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Jagamya Vijayaraghavan, Ph.D.

Jagamya Vijayaraghavan is a technical specialist a part of the firm's Intellectual Property team focusing her work efforts on the biotechnology and life sciences industry. 

Prior to joining Lathrop Gage, Jagamya worked as a postdoctoral fellow at Harvard Medical School where she was involved in expression, purification, protein biochemistry and structural studies of human and bacterial membrane proteins. Jagamya has a very strong background in protein biochemistry, enzymology, structural biology and biophysics.

During her term as a graduate student, Jagamya’s thesis project focused on biochemistry, X-ray crystallography as well as small molecule in silico drug design for mammalian enzymes. She was awarded the NIH Cell and Molecular Biology Training Grant for structure elucidation of human soluble guanylate cyclase. Apart from mammalian enzymes, Jagamya also has an extensive background on structural biology and biochemistry of bacterial proteins. She has been involved in structural studies of both cytoplasmic and integral-membrane bacterial proteins. She has successfully crystallized and solved the structures of a number of bacterial proteins. These structures can now be used to treat bacterial infections and pathogenesis.

Honors

  • National Institute of Health Training Grant for PhD project, 2012 - 2014

Publications

  • Inhibition of Soluble Guanylyl Cyclase by Small Molecules Targeted to the Catalytic Domain. DEBS Lett. 2016 Oct; 590(20): 3669-3680
  • The structure of lytic transglycosylase from Campylobacter jejuni reveals new domain architecture. (Manuscript accepted PlosOne)
  • Substrate Specificity within a Family of Outer Membrane Carboxylate Channels. PLoS Biol 2012; 10(1):e1001242
  • OccK Channels from Pseudomonas aeruginosa Exhibit Diverse Single-channel Electrical Signatures, but Conserved Anion Selectivity. Biochemistry 2012; 20; 51(11):2319-30.
  • Cation selectivity is a conserved feature in the OccD subfamily of Pseudomonas aeruginosa. Biochim Bioshys Acta. 2012; 1818(11):2908-16
Photo of Jagamya  Vijayaraghavan, Ph.D.
  • Boston

    28 State Street
    Suite 700
    Boston, MA 02109
F: 857.300.4001

Assistant

Amanda Vazquez
857.300.4080

Education

Case Western Reserve University, Ph.D. Biochemistry, 2016

Worcester State University, B.S. Biotechnology, magna cum laude, 2009